Semantic contextualisation of social tag-based profiles and item recommendations

Proceedigns of 12th International Conference, EC-Web 2011, Toulouse, France, August 30 - September 1, 2011.The final publication is available at Springer via http://dx.doi.org/10.1007/978-3-642-23014-1_9We present an approach that efficiently identifies the semantic meanings and contexts of social tags within a particular folksonomy, and exploits them to build contextualised tag-based user and item profiles. We apply our approach to a dataset obtained from Delicious social bookmarking system, and evaluate it through two experiments: a user study consisting of manual judgements of tag disambiguation and contextualisation cases, and an offline study measuring the performance of several tag-powered item recommendation algorithms by using contextualised profiles. The results obtained show that our approach is able to accurately determine the actual semantic meanings and contexts of tag annotations, and allow item recommenders to achieve better precision and recall on their predictions.This work was supported by the Spanish Ministry of Science and Innovation (TIN2008-06566-C04-02), and the Community of Madrid (CCG10- UAM/TIC-5877

How tagging pragmatics influence tag sense discovery in social annotation systems

Abstract. The presence of emergent semantics in social annotation systems has been reported in numerous studies. Two important problems in this context are the induction of semantic relations among tags and the discovery of different senses of a given tag. While a number of approaches for discovering tag senses exist, little is known about which factors influence the discovery process. In this paper, we analyze the influence of user pragmatic factors. We divide taggers into different pragmatic distinctions. Based on these distinctions, we identify subsets of users whose annotations allow for a more precise and complete discovery of tag senses. Our results provide evidence for a link between tagging pragmatics and semantics and provide another argument for including pragmatic factors in semantic extraction methods. Our work is relevant for improving search, retrieval and browsing in social annotation systems, as well as for optimizing ontology learning algorithms based on tagging data.

An fMRI study showing the effect of acupuncture in chronic stage stroke patients with aphasia

Acupuncture is used as a treatment in stroke patients with aphasia, yet the underlying neural mechanisms are unknown. This study aims to examine the relationship between changes in language function and brain activation using functional magnetic resonance imaging in chronic stroke patients with aphasia who underwent an 8-week acupuncture protocol. Seven chronic stroke patients were identified from a stroke database of a regional acute hospital in Hong Kong between January and July 2007. Patients were treated three times a week over a period of 8 weeks. Four acupoints were stimulated on the weak side of the patient's body. No other rehabilitation was given during the study period. Changes in language function were measured by aphasia quotient (AQ) of Cantonese Aphasia Battery (CAB). Functional magnetic resonance imaging blood oxygen level dependent signals were used to demonstrate the correlation between changes in AQ and brain activation after treatment. The patients were divided into well-recovered and poorly- recovered groups based on their CAB scores at entry. The well-recovered group showed significant improvement in CAB scores after receiving acupuncture treatment. A significant correlation between changes in AQ and blood oxygen level dependent activation in the lesioned Wernicke's speech area was found. These preliminary results suggest that acupuncture may be beneficial to language recovery in chronic stroke patients. © 2010 Korean Pharmacopuncture Institute.link_to_subscribed_fulltex

Molecular features of non-anaplastic peripheral T-cell lymphoma in children and adolescents

Non-anaplasticperipheral T-cell lymphomas (PTCL) are rare tumors in children, adolescents, and young adults (CAYA) with poor prognosis and scarce genetic data. We analyzed lymphoma tissue from 36 patients up to 18 years old with PTCL, not otherwise specified (PTCL-NOS), hepatosplenic T-cell lymphoma, Epstein-Barr virus (EBV)-positive T-lymphoproliferative diseases, subcutaneous panniculitis-like T-cell lymphoma, and other PTCL types. Twenty-three patients (64%) had at least one genetic variant detectable, including TET2, KMT2C, PIK3D, and DMNT3A. TP53 and RHOA variants, commonly found in adults, were not identified. Eight of 20 (40%) CAYA PTCL-NOS had no detectable mutations. The genetic findings suggest that CAYA PTCL differ from adult cases

Ethnic-specific normative reference values for echocardiographic la and LV size, LV mass, and systolic function: The EchoNoRMAL study

Abstract OBJECTIVES: This study sought to derive age-, sex-, and ethnic-appropriate adult reference values for left atrial (LA) and left ventricular (LV) dimensions and volumes, LV mass, fractional shortening, and ejection fraction (EF) derived from geographically diverse population studies. BACKGROUND: The current recommended reference values for measurements from echocardiography may not be suitable to the diverse world population to which they are now applied. METHODS: Population-based datasets of echocardiographic measurements from 22,404 adults without clinical cardiovascular or renal disease, hypertension, or diabetes were combined in an individual person data meta-analysis. Quantile regression was used to derive reference values at the 95th percentile (upper reference value [URV]) and fifth percentile (lower reference value [LRV]) of each measurement against age (treated as linear), separately within sex and ethnic groups. RESULTS: The URVs for left ventricular end-diastolic volume (LVEDV), LV end-systolic volume, and LV stroke volume (SV) were highest in Europeans and lowest in South Asians. Important sex and ethnic differences remained after indexation by body surface area or height for these measurements, as well as for the LRV for SV. LVEDV and SV decreased with increasing age for all groups. Importantly, the LRV for EF differed by ethnicity; there was a clear apparent difference between Europeans and Asians. The URVs for LV end-diastolic diameter and LV end-systolic diameter were higher for Europeans than those for East Asian, South Asian, and African people, particularly among men. Similarly, the URVs for LA diameter and volume were highest for Europeans. CONCLUSIONS: Sex- and/or ethnic-appropriate echocardiographic reference values are indicated for many measurements of LA and LV size, LV mass, and EF. Reference values for LV volumes and mass also differ across the age range